Glucosamine for Joint Health

Glucosagreen for Joint Health

Joints are essentially the intersection of two bones – allowing our bodies to move, bend and twist. Examples of joints can be found in your fingers, elbows, hip and knees. However, in addition to bone, joints are also comprised of cartilage, ligaments and muscle.

Cartilage is the smooth, rubbery connective tissue that covers the ends of our bones and acts as a cushion for our joints, helping them move smoothly and easily. When force is applied to our joints, such as running, it is cartilage that helps prevent our bones from contacting each other. Our joints are also surrounded by a joint capsule or synovium. This produces a substance called synovial fluid, which both nourishes and lubricates the joint.

After many years of moving and bearing load, it is common for cartilage to deteriorate, meaning the joints’ ability for smooth movement and shock absorption is impaired. Sometimes this can result in pain, and for some, osteoarthritis. In addition, as we age, often our surrounding muscles which move the joint and the bones themselves also deteriorate, providing even more strain and pressure on joints.

Movement is an essential element for health, wellbeing and quality of life. Maintaining joint health is critical to ageing well and maintaining vitality, independence and pain-free movement.

What is Glucosamine?

Glucosamine is naturally produced in the body and is a vital building block of cartilage. It is also found in synovial fluid and plays a key role in stimulating the production of proteoglycans. Proteoglycans allow cartilage to attract and retain water – essential for maintaining lubrication and joint integrity.

As people age, glucosamine levels fall, which may lead to joint degeneration. Consequently, glucosamine can also be taken in the form of a supplement and is one of the world’s most popular treatments for healthy joints. It is available in different forms, with the most common being glucosamine sulfate and glucosamine hydrochloride.

GlucosaGreen for Joint Health – Research

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Glucosamine for Joint Health

Who is it for?

Human Health

  • Individuals wanting to maintain or improve joint health
  • Individuals suffering from osteoarthritis and degenerative joint disease

Animal Health

  • Individuals wanting to maintain or improve joint health
  • Individuals suffering from osteoarthritis and degenerative joint disease
  • Horses, dogs and cats are routinely treated with glucosamine

Glucosagreen for Joint Health – Research

Glucosamine is one of the most commonly used dietary supplements in the world. As such, there are many placebo-controlled trials which have evaluated the efficacy and safety of glucosamine. Overall, glucosamine does compare favourably to ibuprofen for long term reduction of osteoarthritis pain, while simultaneously causing fewer side effects.

Glucosamine is supplied in different forms: glucosamine sulfate, glucosamine hydrochloride or N-acetyl glucosamine. Studies show that while all forms of glucosamine are effective, glucosamine hydrochloride and glucosamine sulfate are the most efficacious. The majority of glucosamine studies recommend a daily dose of 1500mg.

Beyond pain and symptom relief, the effects of glucosamine on progression and joint structure changes have also been evaluated. Multiple randomised, double-blind, placebo-controlled trials demonstrate that long term treatment with glucosamine sulfate is a disease modifying treatment in osteoarthritis, impairing disease progression and positively altering joint structure. Research also confirms glucosamine to be very safe, well tolerated and comparable to placebo.

References:

  1. Reginster, J et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial, The Lancet. 2001; 357:251-256.
  2. Pavelka, K et al. Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis, Arch Intern Med. 2002; 162:2113-2123.
  3. Herrero-Beaumont, G et al. Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: a randomized, double-blind, placebo-controlled study using acetaminophen as a side comparator, Arthritis Rheum. 2007; Feb;56(2):555-67.
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